Description
Fentanyl Ampoule Injection 500mcg/10ml
Description:
Fentanyl Injection 500mcg/10ml is a potent opioid analgesic used for various purposes, including anesthesia and pain management. It contains fentanyl citrate as the active ingredient. Fentanyl is known for its high potency and rapid onset of action, making it effective for managing severe pain.
Key Features:
– Strength: Each 10ml vial of Fentanyl Injection contains 500mcg (micrograms) of fentanyl citrate.
– Administration: Fentanyl Injection is intended for intravenous or intramuscular use.
– Indications: It is indicated for analgesic action during anesthesia, premedication, induction and maintenance, and in the immediate postoperative period. It can also be used as an opioid analgesic supplement in general or regional anesthesia. Additionally, it may be administered with a neuroleptic as an anesthetic premedication or as an adjunct in the maintenance of general and regional anesthesia. Fentanyl Injection can be used as an anesthetic agent with oxygen in selected high-risk patients, such as those undergoing open heart surgery or certain complicated neurological or orthopedic procedures.
– Dosage and Administration: Fentanyl Injection should be administered only by individuals specifically trained in the use of intravenous anesthetics and management of the respiratory effects of potent opioids. The dosage should be individualized based on age, body weight, physical status, underlying pathological condition, use of other drugs, type of anesthesia, and the surgical procedure involved. The initial treatment for adults is typically 50 to 100 mcg (0.05 to 0.1 mg) (1 to 2 mL), while children aged 2 to 12 years may require a reduced dose as low as 2 to 3 mcg/kg.
– Contraindications: Fentanyl Injection is contraindicated in individuals with a known hypersensitivity to fentanyl.
– Warnings and Precautions: Fentanyl Injection carries serious and life-threatening risks, including addiction, abuse, and misuse. It may cause respiratory depression, especially during initiation or following a dosage increase. Concomitant use with benzodiazepines or other central nervous system depressants, as well as CYP3A4 inhibitors, can result in profound sedation, respiratory depression, coma, and death. Skeletal muscle rigidity and movement, severe cardiovascular depression, opioid-induced hyperalgesia, serotonin syndrome, adrenal insufficiency, and risks in patients with increased intracranial pressure or gastrointestinal conditions should also be considered.
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